Nos publications scientifiques

 
Oral Aphthous: Pathophysiology, Clinical Aspects and Medical Treatment.
Gasmi Benahmed A, Noor S, Menzel A, Gasmi A.Arch Razi Inst. 2021 Nov 30;76(5):1155-1163. doi: 10.22092/ari.2021.356055.1767. eCollection 2021 Nov.PMID: 35355774 Free PMC article. Review.
For oral aphthous or recurrent aphthous ulcers from an underlying disease, topical medications are preferred due to their minimum side effects. Systemic medications are necessary if the disease progresses. …
 
Health benefits of xylitol.
Gasmi Benahmed A, Gasmi A, Arshad M, Shanaida M, Lysiuk R, Peana M, Pshyk-Titko I, Adamiv S, Shanaida Y, Bjørklund G.Appl Microbiol Biotechnol. 2020 Sep;104(17):7225-7237. doi: 10.1007/s00253-020-10708-7. Epub 2020 Jul 7.PMID: 32638045 Review.
Xylitol can reduce constipation, diabetes, obesity, and other body syndromes or illnesses; it has also revealed its stimulating effect on digestion and immune system. However, it can produce some side effects such as irritable bowel syndrome, diarrhea, nephrolithiasis, etc 
 
A review on natural teeth whitening.
Gasmi Benahmed A, Gasmi A, Menzel A, Hrynovets I, Chirumbolo S, Shanaida M, Lysiuk R, Shanaida Y, Dadar M, Bjørklund G.J Oral Biosci. 2022 Mar;64(1):49-58. doi: 10.1016/j.job.2021.12.002. Epub 2021 Dec 13.PMID: 34915121 Review.
If used extensively, these compounds may cause a number of adverse effects. Alternative natural teeth-whiteners include ingredients like lemons, strawberries, oranges, papaya, and other fruits. …
 
Natural Compounds Used for Treating Hair Loss.
Gasmi A, Mujawdiya PK, Beley N, Shanaida M, Lysiuk R, Lenchyk L, Noor S, Muhammad A, Strus O, Piscopo S, Komisarenko A, Fedorovska M, Bjørklund G.Curr Pharm Des. 2023;29(16):1231-1244. doi: 10.2174/1381612829666230505100147.PMID: 37151166 Review.
Various treatments for hair loss, including both synthetic drugs, such as minoxidil and finasteride, or medicinal herbs, have been approved by the Food and Drug Administration. Despite synthetic drugs’ effectiveness, they may come with potential side effects. …As …
 
Natural Ingredients to Improve Immunity.
Gasmi A, Shanaida M, Oleshchuk O, Semenova Y, Mujawdiya PK, Ivankiv Y, Pokryshko O, Noor S, Piscopo S, Adamiv S, Bjørklund G.Pharmaceuticals (Basel). 2023 Apr 1;16(4):528. doi: 10.3390/ph16040528.PMID: 37111285 Free PMC article. Review
 
Polyphenols in Metabolic Diseases.
Gasmi A, Mujawdiya PK, Noor S, Lysiuk R, Darmohray R, Piscopo S, Lenchyk L, Antonyak H, Dehtiarova K, Shanaida M, Polishchuk A, Shanaida V, Peana M, Bjørklund G.Molecules. 2022 Sep 23;27(19):6280. doi: 10.3390/molecules27196280.PMID: 36234817 Free PMC article. Review.
They possess powerful antioxidant properties, multiple therapeutic effects, and possible health benefits in vivo and in vitro, as well as reported clinical studies. …
 
Interrelations between COVID-19 and other disorders.
Gasmi A, Peana M, Pivina L, Srinath S, Gasmi Benahmed A, Semenova Y, Menzel A, Dadar M, Bjørklund G.Clin Immunol. 2021 Mar;224:108651. doi: 10.1016/j.clim.2020.108651. Epub 2020 Dec 14.PMID: 33333255 Free PMC article. Review.
 
Metabolic Conditions and Peri-Implantitis.
Gasmi Benahmed A, Gasmi A, Tippairote T, Mujawdiya PK, Avdeev O, Shanaida Y, Bjørklund G.Antibiotics (Basel). 2022 Dec 29;12(1):65. doi: 10.3390/antibiotics12010065.PMID: 36671266 Free PMC article. Review.
Chronic periodontitis, low-grade tissue inflammation, and increased oxidative stress raise the incidence of PI and the underlying systemic metabolic conditions, such as obesity, diabetes mellitus, or harmful lifestyle factors (cigarette smoking, etc.). Using dental biomaterials w …
 
Hallmarks of Periodontitis.
Gasmi Benahmed A, Gasmi A, Noor S, Semenova Y, Emadali A, Dadar M, Shanaida Y, Avdeev O, Bjørklund G.Curr Med Chem. 2024 May 16. doi: 10.2174/0109298673302701240509103537. Online ahead of print.PMID: 38757324
 
Gut microbiota in bariatric surgery.
Gasmi A, Bjørklund G, Mujawdiya PK, Semenova Y, Dosa A, Piscopo S, Pen JJ, Gasmi Benahmed A, Costea DO.Crit Rev Food Sci Nutr. 2023;63(28):9299-9314. doi: 10.1080/10408398.2022.2067116. Epub 2022 May 9.PMID: 35531940 Review.
 
Neurological Involvements of SARS-CoV2 Infection.
Gasmi A, Tippairote T, Mujawdiya PK, Gasmi Benahmed A, Menzel A, Dadar M, Bjørklund G.Mol Neurobiol. 2021 Mar;58(3):944-949. doi: 10.1007/s12035-020-02070-6. Epub 2020 Oct 16.PMID: 33064267 Free PMC article. Review.
 
Dietary supplements and bariatric surgery.
Gasmi A, Bjørklund G, Mujawdiya PK, Semenova Y, Dosa A, Piscopo S, Pen JJ, Gasmi Benahmed A, Costea DO.Crit Rev Food Sci Nutr. 2023;63(25):7477-7488. doi: 10.1080/10408398.2022.2046542. Epub 2022 Apr 15.PMID: 35426325 Review.
 
Nutrients Interaction with the Immune System.
Noor S, Piscopo S, Gasmi A.Arch Razi Inst. 2021 Dec 30;76(6):1579-1588. doi: 10.22092/ari.2021.356098.1775. eCollection 2021 Dec.PMID: 35546980 Free PMC article. Review.
In conclusion, all the components of our daily diet are associated with the development of the immune system, and understanding their interactions is important for future immune therapies and drug development….
 
Coenzyme Q10 in aging and disease.
Gasmi A, Bjørklund G, Mujawdiya PK, Semenova Y, Piscopo S, Peana M.Crit Rev Food Sci Nutr. 2024;64(12):3907-3919. doi: 10.1080/10408398.2022.2137724. Epub 2022 Oct 27.PMID: 36300654 Review.
Oral supplementation with high doses of CoQ(10) can increase both its circulating and intracellular levels and several clinical trials observed that its administration provided beneficial effects on different disorders such as cardiovascular disease and inflammation which …
 
Nutritional and surgical aspects in prostate disorders.
Gasmi A, Bjørklund G, Noor S, Semenova Y, Dosa A, Pen JJ, Menzel A, Piscopo S, Wirth N, Costea DO.Crit Rev Food Sci Nutr. 2023;63(21):5138-5154. doi: 10.1080/10408398.2021.2013158. Epub 2022 Jan 12.PMID: 35021909 Review.
Finally, we propose nutrition-based treatment in each of these prostate problems, based on in-depth research concerning its effects in this context, with an emphasis on surgery. Overall, we plead for an upgrade of this form of alternative treatment to a fully recognized mo …
 
Potential drugs in COVID-19 management.
Gasmi A, Noor S, Menzel A, Khanyk N, Semenova Y, Lysiuk R, Beley N, Bolibrukh L, Gasmi Benahmed A, Storchylo O, Bjørklund G.Curr Med Chem. 2023 Jul 17. doi: 10.2174/0929867331666230717154101. Online ahead of print.PMID: 37461346
The SARS-CoV-2 virus first emerged in China in December 2019 and quickly spread worldwide. Despite the absence of a vaccination or authorized drug specifically developed to combat this infection, certain medications recommended for other diseases have shown potential effec …
The microbiota-mediated dietary and nutritional interventions for COVID-19.
Gasmi A, Tippairote T, Mujawdiya PK, Peana M, Menzel A, Dadar M, Benahmed AG, Bjørklund G.Clin Immunol. 2021 May;226:108725. doi: 10.1016/j.clim.2021.108725. Epub 2021 Apr 9.PMID: 33845194 Free PMC article. Review.
This narrative review explores the recent studies on dietary, nutritional, and lifestyle interventions that influence the microbiota-mediated immunomodulatory effects against viral infections. Cumulative studies reported that the airway microbiota and SARS-CoV-2 leverage e …
 
Berberine: Pharmacological Features in Health, Disease and Aging.
Gasmi A, Asghar F, Zafar S, Oliinyk P, Khavrona O, Lysiuk R, Peana M, Piscopo S, Antonyak H, Pen JJ, Lozynska I, Noor S, Lenchyk L, Muhammad A, Vladimirova I, Dub N, Antoniv O, Tsal O, Upyr T, Bjørklund G.Curr Med Chem. 2024;31(10):1214-1234. doi: 10.2174/0929867330666230207112539.PMID: 36748808 Review.
BACKGROUND: Berberine is the main active compound of different herbs and is defined as an isoquinoline quaternary botanical alkaloid found in barks and roots of numerous plants. It exhibits a wide range of pharmacological effects, such as anti-obesity and antidiabetic e
 
Lifestyle Genetics-Based Reports in the Treatment of Obesity.
Gasmi A, Mujawdiya PK, Noor S, Piscopo S, Menzel A.Arch Razi Inst. 2021 Oct 31;76(4):707-719. doi: 10.22092/ari.2021.356057.1768. eCollection 2021 Oct.PMID: 35096307 Free PMC article. Review.
Due to a lack of effective strategies for prevention and management, the adverse effects of obesity and related diseases on health continue to be a serious problem. …
 
Association between the gut and oral microbiome with obesity.
Gasmi Benahmed A, Gasmi A, Doşa A, Chirumbolo S, Mujawdiya PK, Aaseth J, Dadar M, Bjørklund G.Anaerobe. 2021 Aug;70:102248. doi: 10.1016/j.anaerobe.2020.102248. Epub 2020 Aug 14.PMID: 32805390 Review.
The oral microbiome has also been implicated in the development of obesity due to its modulating effects on the gut microbiome. Due to its critical role in obesity, alteration in the gut microbiome has been suggested as one of the therapeutic strategies to manage obesity i …
 
Neurotransmitters Regulation and Food Intake: The Role of Dietary Sources in Neurotransmission.
Gasmi A, Nasreen A, Menzel A, Gasmi Benahmed A, Pivina L, Noor S, Peana M, Chirumbolo S, Bjørklund G.Molecules. 2022 Dec 26;28(1):210. doi: 10.3390/molecules28010210.PMID: 36615404 Free PMC article. Review.
These molecules are synthesized from simple, very common precursors. Many types of NTs have both excitatory and inhibitory effects. Neurotransmitters’ imbalance can cause many diseases and disorders, such as Parkinson’s disease, depression, insomnia, increased anxiety, mem …
 
Herbal Treatments for Obesity: A Review.
Gasmi A, Noor S, Mujawdiya PK, Akram M, Manzoor A, Bjørklund G.Curr Med Chem. 2024 Mar 20. doi: 10.2174/0109298673287491240315055726. Online ahead of print.PMID: 38509683
FDA-approved obesity-controlling drugs are effective but possess certain adverse effects, including dry mouth, drug abuse, dysregulation in monoamine neurotransmitters, insomnia, and many more. …All of these herbs are responsible for anti-obesity, anti-diabetic, a …
 
Ayurvedic and Chinese Herbs against Coronaviruses.
Gasmi A, Kanwal S, Oliinyk P, Lysiuk R, Shanaida M, Gasmi Benahmed A, Dushmantha WKT, Arshad M, Kernychna I, Lenchyk L, Upyr T, Shanaida V, Bjørklund G.Curr Pharm Des. 2024 Apr 29. doi: 10.2174/0113816128269864231112094917. Online ahead of print.PMID: 38685809
 
Quercetin in the Prevention and Treatment of Coronavirus Infections: A Focus on SARS-CoV-2.
Gasmi A, Mujawdiya PK, Lysiuk R, Shanaida M, Peana M, Gasmi Benahmed A, Beley N, Kovalska N, Bjørklund G.Pharmaceuticals (Basel). 2022 Aug 25;15(9):1049. doi: 10.3390/ph15091049.PMID: 36145270 Free PMC article. Review.
QR is an active agent against SARS and MERS due to its antimicrobial, antiviral, anti-inflammatory, antioxidant, and some other beneficial effects. QR may hold therapeutic potential against SARS-CoV-2 due to its inhibitory effects on several stages of the viral life …
 
Toxic Metals Exposure and APOE4 Gene Variant in Cognitive Decline Disorders.
Gasmi A, Menzel A, Piscopo S, Noor S.Arch Razi Inst. 2022 Feb 28;77(1):1-10. doi: 10.22092/ARI.2021.356078.1771. eCollection 2022 Feb.PMID: 35891722 Free PMC article. Review.
Misfolding of proteins especially apolipoprotein E is a key genetic factor involved in several cognitive impairments. Increasing evidence also described the toxic effects of metals, generated by both nature and humans, on the development of neurological disorders. …These …
 
Chloroquine and hydroxychloroquine in the treatment of COVID-19: the never-ending story.
Gasmi A, Peana M, Noor S, Lysiuk R, Menzel A, Gasmi Benahmed A, Bjørklund G.Appl Microbiol Biotechnol. 2021 Feb;105(4):1333-1343. doi: 10.1007/s00253-021-11094-4. Epub 2021 Jan 30.PMID: 33515285 Free PMC article. Review.
The anti-malarial drugs chloroquine (CQ) and hydroxychloroquine (HCQ) have been suggested as promising agents against the new coronavirus SARS-CoV-2 that induces COVID-19 and as a possible therapy for shortening the duration of the viral disease. The antiviral effects of C …
 
The Possible Roles of β-alanine and L-carnosine in Anti-aging.
Gasmi A, Mujawdiya PK, Lysiuk R, Shanaida M, Peana M, Piscopo S, Beley N, Dzyha S, Smetanina K, Shanaida V, Résimont S, Bjørklund G.Curr Med Chem. 2024 Jan 12. doi: 10.2174/0109298673263561231117054447. Online ahead of print.PMID: 38243982
alanine (BA), being a non-proteinogenic amino acid, is an important constituent of L-carnosine (LC), which is necessary for maintaining the muscle buffering capacity and preventing a loss of muscle mass associated with aging effects. BA is also very important for normal hu …
 
The role of sugar-rich diet and salivary proteins in dental plaque formation and oral health.
Gasmi Benahmed A, Gasmi A, Dadar M, Arshad M, Bjørklund G.J Oral Biosci. 2021 Jun;63(2):134-141. doi: 10.1016/j.job.2021.01.007. Epub 2021 Jan 23.PMID: 33497842 Review.
CONCLUSION: The oral microbiota is essential for maintaining and reestablishing a healthy oral cavity. Different types of sugars have different effects on the inhibition and formation of dental plaque. The peptides, proteins, and amino acids secreted by parotid glands in t …
 
The Role of Traditional Chinese Medicine and Chinese Pharmacopoeia in the Evaluation and Treatment of COVID-19.
Gasmi A, Noor S, Dadar M, Semenova Y, Menzel A, Gasmi Benahmed A, Bjørklund G.Curr Pharm Des. 2024;30(14):1060-1074. doi: 10.2174/0113816128217263240220060252.PMID: 38523518 Review.
Thus, there is a need to develop alternative options. TCM has demonstrated positive effects in the treatment of COVID-19. Previous research studies on TCM showed broad-spectrum antiviral activity, offering a range of possibilities for their potential use against COVID-19. …
 
Anticancer activity of broccoli, its organosulfur and polyphenolic compounds.
Gasmi A, Gasmi Benahmed A, Shanaida M, Chirumbolo S, Menzel A, Anzar W, Arshad M, Cruz-Martins N, Lysiuk R, Beley N, Oliinyk P, Shanaida V, Denys A, Peana M, Bjørklund G.Crit Rev Food Sci Nutr. 2023 May 2:1-19. doi: 10.1080/10408398.2023.2195493. Online ahead of print.PMID: 37129118
Consumption of broccoli-derived phytochemicals provides strong antioxidant effects, particularly due to its sulforaphane content, while modulating numerous molecules involved in cell cycle regulation, control of apoptosis, and tuning enzyme activity. …
 
Optimizing the Antimicrobial Effects by using Natural Compounds in COVID-19 Management.
Gasmi A, Benahmed AG, Dadar M, Mujawdiya P, Bjørklund G.Curr Med Chem. 2024 May 23. doi: 10.2174/0109298673294083240520044158. Online ahead of print.PMID: 38797911
Alternatively, novel therapeutic strategies can be explored to enhance the antimicrobial effects of the existing antimicrobial agents, such as antibiotics. …Natural compounds are generally considered safe and may even reduce the side effects of drugs and medicines …